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Pathology · Neoplasia
Sample itemWhat is a tumour suppressor gene's normal role?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Limit cell proliferation or promote repair and apoptosis
Tumour suppressor genes restrain proliferation, repair DNA damage, or promote apoptosis, so their loss can contribute to cancer development.
Option by option
A. Limit cell proliferation or promote repair and apoptosis (correct)
Correct: they normally protect against inappropriate growth.
B. Encode all antibody proteins
Antibody genes are not the general role of tumour suppressors.
C. Transport oxygen in red cells
Haemoglobin transports oxygen, not tumour suppressors.
D. Increase uncontrolled cell division
Uncontrolled proliferation results when suppression is lost.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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