Hepatic pathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Hepatic pathology

Sample item

Which structural change defines established cirrhosis of the liver?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Diffuse fibrosis with regenerative nodules disrupting liver architecture

Cirrhosis is diffuse hepatic fibrosis with regenerative nodules that distort normal architecture and can cause portal hypertension and liver failure.

Option by option

  • A. Diffuse fibrosis with regenerative nodules disrupting liver architecture (correct)

    Correct: fibrosis and nodules reshape the liver diffusely.

  • B. Simple excess bile in the intestine

    Intestinal bile does not define cirrhosis.

  • C. Acute reversible liver swelling only

    Reversible swelling is not cirrhosis.

  • D. A benign gallbladder polyp

    Gallbladder polyps are a different organ pathology.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is A, Diffuse fibrosis with regenerative nodules disrupting liver architecture. Cirrhosis is diffuse hepatic fibrosis with regenerative nodules that distort normal architecture and can cause portal hypertension and liver failure.

Why is "Simple excess bile in the intestine" not the answer?

Intestinal bile does not define cirrhosis.

Why is "Acute reversible liver swelling only" not the answer?

Reversible swelling is not cirrhosis.

Why is "A benign gallbladder polyp" not the answer?

Gallbladder polyps are a different organ pathology.

What concept does this question test?

It tests Hepatic pathology in Pathology. The correct option holds because: Correct: fibrosis and nodules reshape the liver diffusely.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hepatic pathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.