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PSM · Study design
Sample itemWhy is blinding used in randomized trials?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Reduce differential behaviour or outcome assessment bias
Blinding reduces the chance that expectations alter cointerventions, reporting, assessment, or interpretation of outcomes between trial groups.
Option by option
A. Replace random allocation
It complements rather than replaces randomization.
B. Increase disease prevalence
Blinding does not change underlying prevalence.
C. Avoid obtaining consent
Consent remains required in ethical research.
D. Reduce differential behaviour or outcome assessment bias (correct)
Correct: blinding protects against expectation-related bias.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.