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Dermatology · Rosacea
Sample itemA 40-year-old woman has episodic flushing with persistent central facial erythema, telangiectasia and papules and pustules, but no comedones. Symptoms worsen with alcohol and hot drinks. Which topical agent is commonly used for the inflammatory lesions?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Metronidazole gel
Rosacea is a chronic inflammatory disease of the central face, in which absence of comedones separates it from acne. Triggers such as heat, alcohol and sunlight should be avoided, and topical metronidazole, azelaic acid or ivermectin are used for papulopustular disease. Potent topical steroids can aggravate it.
Option by option
A. Benzoyl peroxide 10 percent as the only treatment for flushing
Benzoyl peroxide targets comedonal acne and does not treat the flushing and background erythema.
B. Tretinoin cream
Tretinoin may irritate rosacea and does not address the vascular component.
C. Metronidazole gel (correct)
Correct. Metronidazole gel is a standard treatment for inflammatory lesions.
D. Clobetasol propionate cream
Potent steroids cause steroid rosacea and worsen the condition.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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