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Dermatology · Cutaneous tuberculosis
Sample itemA 20-year-old woman has a slowly enlarging reddish-brown plaque on her cheek for several years. On diascopy with a glass slide, the lesion shows an apple-jelly colour. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Lupus vulgaris
Lupus vulgaris is a common form of cutaneous tuberculosis in India, with slowly progressive, soft, reddish-brown plaques and nodules, usually on the face, and an apple-jelly colour on diascopy. Biopsy shows tuberculoid granulomas, and treatment is standard antitubercular therapy.
Option by option
A. Discoid lupus erythematosus
Discoid lupus gives scaly atrophic plaques with follicular plugging and scarring.
B. Lepromatous leprosy
Lepromatous leprosy gives multiple symmetrical infiltrated nodules and loss of eyebrows.
C. Lupus vulgaris (correct)
Correct. Apple-jelly nodules on diascopy are characteristic.
D. Lupus pernio of sarcoidosis
Lupus pernio of sarcoidosis gives violaceous plaques on the nose and cheeks, and is also granulomatous but is usually violaceous.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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