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Dermatology · Drug reactions: corticosteroid-induced acne
Sample itemA man started on high-dose oral prednisolone for nephrotic syndrome develops, within two weeks, an abrupt crop of uniform red papules and pustules on the chest and back without blackheads. What is the best interpretation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Steroid acne, a monomorphic follicular eruption without comedones
Corticosteroids can provoke a monomorphic eruption of inflammatory papules and pustules, mainly on the trunk, appearing within weeks, without comedones. Malassezia may contribute. Treatment is topical retinoids, benzoyl peroxide or antibiotics and, if possible, dose reduction.
Option by option
A. Bacterial folliculitis from Pseudomonas
Pseudomonas folliculitis follows hot tub exposure and is not tied to steroid therapy.
B. Acne vulgaris with a typical polymorphic picture
Acne vulgaris has comedones and evolves over months with lesions at different stages.
C. Steroid acne, a monomorphic follicular eruption without comedones (correct)
Correct. A sudden monomorphic eruption without comedones after steroids is steroid acne.
D. Tinea corporis
Tinea corporis gives scaly annular plaques with central clearing.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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