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Dentistry · Oral pathology: cysts and odontogenic tumours: periapical granuloma
Sample itemA non-vital tooth is extracted with a soft tissue mass at the root tip. Histology shows granulation tissue with lymphocytes and plasma cells and proliferating epithelial rests, but no epithelium-lined cavity and no pus. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Periapical granuloma
A periapical granuloma is chronic inflammatory granulation tissue at the apex of a non-vital tooth. A radicular cyst has an epithelium-lined cavity, an abscess is a collection of pus, and cemental dysplasia occurs at the apices of vital teeth.
Option by option
A. Periapical abscess
An abscess contains a collection of pus with neutrophils and tissue breakdown.
B. Periapical cemental dysplasia
Cemental dysplasia is a fibro-osseous change at vital teeth, not a response to necrosis.
C. Periapical granuloma (correct)
Correct. Chronic inflammatory granulation tissue without a lined cavity is a granuloma.
D. Radicular cyst
A radicular cyst needs a cavity lined by epithelium and filled with fluid.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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