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Dentistry · Oral pathology: cysts and odontogenic tumours: ameloblastic fibroma
Sample itemA 10-year-old has a well-defined radiolucency in the posterior mandible. Histology shows strands and islands of epithelium resembling dental lamina in a cellular, primitive mesenchyme resembling dental papilla, with no enamel or dentine. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Ameloblastic fibroma
Ameloblastic fibroma is a mixed tumour with both epithelial and mesenchymal components that occurs mainly in children and young adults in the posterior mandible. It lacks hard tissue and is treated with conservative excision, with follow-up for recurrence.
Option by option
A. Central odontogenic fibroma
Central odontogenic fibroma is mainly fibrous tissue with scattered epithelial islands.
B. Odontogenic myxoma
Odontogenic myxoma is mostly myxoid stroma with a few odontogenic epithelial rests.
C. Ameloblastic fibroma (correct)
Correct. Both components without enamel or dentine point to ameloblastic fibroma.
D. Ameloblastic fibro-odontoma
Ameloblastic fibro-odontoma has the same pattern plus enamel and dentine.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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