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Dentistry · Oral pathology: cysts and odontogenic tumours: amyloid in Pindborg tumour
Sample itemSections of a calcifying epithelial odontogenic tumour contain homogeneous eosinophilic extracellular material thought to be amyloid-like. Which stain shows apple-green birefringence under polarised light?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Congo red
Amyloid is stained by Congo red and shows apple-green birefringence under polarised light. This amyloid-like material in the Pindborg tumour may calcify to form Liesegang rings. PAS stains glycogen, Alcian blue stains mucin and von Kossa stains calcium.
Option by option
A. Congo red (correct)
Correct. Congo red with polarised light gives apple-green birefringence in amyloid.
B. Von Kossa
Von Kossa stains calcium deposits.
C. Alcian blue
Alcian blue stains acidic mucins.
D. Periodic acid-Schiff
PAS stains glycogen and basement membranes, not amyloid.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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