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Dentistry · Oral and maxillofacial surgery and facial fractures: tetanus prophylaxis in facial wounds
Sample itemA farmer has a soil-contaminated facial laceration after a fall and has never received tetanus vaccination. Which prophylaxis is appropriate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Tetanus toxoid with human tetanus immunoglobulin at separate sites
For a tetanus-prone wound in an unimmunised patient, passive protection with human tetanus immunoglobulin is given together with active immunisation using toxoid, at different sites with separate syringes. Wound cleaning and debridement remain essential.
Option by option
A. Oral antibiotics alone
Antibiotics do not neutralise the toxin and are not a substitute.
B. Tetanus toxoid alone
Toxoid alone takes time to produce antibodies and does not give immediate protection.
C. Tetanus immunoglobulin alone
Immunoglobulin alone gives short-lived protection without starting active immunity.
D. Tetanus toxoid with human tetanus immunoglobulin at separate sites (correct)
Correct. Both passive and active immunisation are needed in an unimmunised patient with a dirty wound.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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