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Dermatology · Infections: bacterial, viral, fungal, parasitic: primary cutaneous aspergillosis
Sample itemA neutropenic patient develops an erythematous plaque with a black central eschar around an intravenous cannula site. Biopsy shows septate hyphae branching at acute angles. Which organism is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Aspergillus species
Aspergillus forms septate hyphae that branch dichotomously at about 45 degrees, and primary cutaneous disease occurs at IV sites or burns in neutropenic hosts. Treatment is surgical debridement with voriconazole.
Option by option
A. Aspergillus species (correct)
Correct. Acute-angle branching septate hyphae characterise Aspergillus.
B. Candida albicans
Candida appears as yeasts and pseudohyphae, not branching septate hyphae.
C. Sporothrix schenckii
Sporothrix forms cigar-shaped yeasts in tissue, not branching hyphae.
D. Rhizopus species
Rhizopus is a mucormycete with broad aseptate hyphae branching at right angles.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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