Try it
Dermatology · Skin tumours: acral melanoma
Sample itemA 55-year-old Indian man has a darkly pigmented, irregular, enlarging macule on the sole. Which melanoma subtype is the most common in dark-skinned populations such as Indians?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Acral lentiginous melanoma
In Asian and African populations, melanoma most commonly arises on the palms, soles and subungual areas as acral lentiginous melanoma. Any changing pigmented lesion at these sites requires biopsy.
Option by option
A. Amelanotic melanoma
Amelanotic melanoma is a pigment-poor variant and not the commonest subtype.
B. Lentigo maligna melanoma
Lentigo maligna arises on chronically sun-damaged facial skin of the elderly.
C. Acral lentiginous melanoma (correct)
Correct. Acral lentiginous melanoma predominates in darker skin.
D. Superficial spreading melanoma
Superficial spreading melanoma is most common in fair-skinned people.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Dermatology questions
- Blistering disordersA patient has flaccid blisters that rupture easily and a positive Nikolsky sign. Which c…
- LeprosyIn which type of leprosy is the lepromin test strongly positive?
- Pigmentary disordersA man has well-demarcated chalk-white macules on his hands and around his mouth. A skin…
- Drug reactionsWhich of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome an…