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Dermatology · Bacterial infections: necrotising fasciitis
Sample itemA diabetic woman has a rapidly spreading red leg with pain out of proportion, dusky skin, bullae and fever with hypotension. What is the most important immediate step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Urgent surgical exploration and debridement with broad-spectrum antibiotics
Pain out of proportion, rapid spread and systemic toxicity suggest necrotising fasciitis, a surgical emergency. Early debridement with broad-spectrum antibiotics covering streptococci, anaerobes and gram-negatives is life-saving, and imaging must not delay it.
Option by option
A. Urgent surgical exploration and debridement with broad-spectrum antibiotics (correct)
Correct. Surgery is the cornerstone and should not be delayed.
B. Elevation of the limb and topical antibiotics
Elevation and topical agents do not reach the deep fascial infection.
C. Oral antibiotics with review in 48 hours
Oral antibiotics with a delay allow rapid progression and death.
D. Delay treatment until an MRI is done
Delaying for imaging increases mortality; diagnosis is clinical with surgical confirmation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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