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Dermatology · Infestations: onchocerciasis
Sample itemA patient from an endemic African region has subcutaneous nodules, severe itching with lichenified skin, depigmentation over the shins and visual impairment. Which drug is used for mass treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Ivermectin
Onchocerca volvulus is transmitted by Simulium blackflies and causes dermatitis, leopard skin and river blindness. Annual ivermectin kills microfilariae and is used for community treatment.
Option by option
A. Rifampicin
Rifampicin treats mycobacterial infection.
B. Griseofulvin
Griseofulvin is an antifungal.
C. Ivermectin (correct)
Correct. Ivermectin is the mass treatment drug.
D. Praziquantel
Praziquantel is used for schistosomiasis and cestodes.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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