Papulosquamous disorders: lichen sclerosus: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Papulosquamous disorders: lichen sclerosus

Sample item

A postmenopausal woman has intense vulval itching with porcelain-white atrophic plaques in a figure-of-eight around the vulva and anus. What is the first-line treatment?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Ultrapotent topical corticosteroid such as clobetasol

Lichen sclerosus is a chronic inflammatory disease with a small risk of squamous cell carcinoma, and clobetasol propionate 0.05 percent is the first-line treatment with long-term follow-up. In men, it causes balanitis xerotica obliterans.

Option by option

  • A. Topical antibiotics

    Antibiotics are not indicated without infection.

  • B. Oral griseofulvin

    Griseofulvin treats dermatophyte infection.

  • C. Ultrapotent topical corticosteroid such as clobetasol (correct)

    Correct. Ultrapotent topical steroids control disease.

  • D. Topical estrogen alone

    Estrogen alone does not treat the condition.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is C, Ultrapotent topical corticosteroid such as clobetasol. Lichen sclerosus is a chronic inflammatory disease with a small risk of squamous cell carcinoma, and clobetasol propionate 0.

Why is "Topical antibiotics" not the answer?

Antibiotics are not indicated without infection.

Why is "Oral griseofulvin" not the answer?

Griseofulvin treats dermatophyte infection.

Why is "Topical estrogen alone" not the answer?

Estrogen alone does not treat the condition.

What concept does this question test?

It tests Papulosquamous disorders: lichen sclerosus in Dermatology. 05 percent is the first-line treatment with long-term follow-up. In men, it causes balanitis xerotica obliterans.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Papulosquamous disorders: lichen sclerosus?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.