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Dermatology · Bullous disorders: mucous membrane pemphigoid
Sample itemAn elderly woman has desquamative gingivitis and recurrent conjunctivitis with adhesions between the eyelid and eyeball. Which complication is most feared?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Blindness from scarring (symblepharon)
Mucous membrane pemphigoid is a scarring subepidermal blistering disease of the mucosae and requires ophthalmology review. Cyclophosphamide or rituximab is used in severe ocular disease, with dapsone for mild disease.
Option by option
A. Blindness from scarring (symblepharon) (correct)
Correct. Ocular scarring can cause blindness.
B. Heart block
Heart block is not a feature.
C. Renal tubular acidosis
Renal tubular acidosis is not a feature.
D. Hepatic failure
Hepatic failure is not a feature.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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