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Dermatology · Leprosy: indeterminate leprosy
Sample itemA child has a single ill-defined hypopigmented macule with minimal sensory loss and no nerve thickening. Biopsy shows a nonspecific infiltrate around neurovascular bundles. What is this stage called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Indeterminate leprosy
Indeterminate leprosy is the earliest clinical presentation, and may heal spontaneously or evolve along the spectrum depending on host immunity. Treatment follows the paucibacillary regimen.
Option by option
A. Lepromatous leprosy
Lepromatous leprosy shows multiple symmetric lesions with foamy macrophages.
B. Histoid leprosy
Histoid leprosy has firm nodules with spindle cells.
C. Tuberculoid leprosy
Tuberculoid leprosy has a well-defined anaesthetic plaque with granulomas.
D. Indeterminate leprosy (correct)
Correct. A single early macule with nonspecific histology fits.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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