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Dermatology · STI: epididymo-orchitis
Sample itemA 24-year-old sexually active man has acute unilateral scrotal pain and swelling with urethral discharge. Which organisms are most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Neisseria gonorrhoeae and Chlamydia trachomatis
In sexually active men under 35, epididymo-orchitis is usually due to gonorrhoea or chlamydia and is treated with ceftriaxone and doxycycline. In older men or after anal intercourse, enteric organisms such as E. coli are more common.
Option by option
A. Escherichia coli
E. coli is typical in older men with urinary tract abnormalities.
B. Mumps virus only
Mumps orchitis follows parotitis, not urethral discharge.
C. Mycobacterium tuberculosis
Tuberculosis causes a chronic painless epididymal mass.
D. Neisseria gonorrhoeae and Chlamydia trachomatis (correct)
Correct. Sexually transmitted pathogens dominate in young men.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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