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Dentistry · Oral medicine: oral hairy leukoplakia
Sample itemA patient with HIV has a corrugated white lesion of the lateral tongue that cannot be scraped off. What is the likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Epstein-Barr virus
Oral hairy leukoplakia is an EBV-driven lesion on the lateral tongue in immunosuppressed people, especially with HIV. It does not scrape off and is not itself premalignant.
Option by option
A. Candida albicans
Candidiasis wipes off.
B. Herpes simplex virus
HSV causes vesicles and ulcers.
C. Human papillomavirus type 16
HPV 16 is linked with oropharyngeal carcinoma.
D. Epstein-Barr virus (correct)
Correct. EBV replication causes hairy leukoplakia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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