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Dentistry · Oral medicine and oral cancer: biopsy technique
Sample itemA 55-year-old tobacco chewer has a 1.5 cm indurated ulcer on the lateral tongue that has not healed for 4 weeks. What is the best next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Incisional biopsy from the edge including adjacent normal mucosa
A non-healing ulcer longer than 3 weeks is cancer until proven otherwise. An incisional biopsy from the margin, avoiding necrotic centre, gives the diagnosis.
Option by option
A. Cryotherapy of the ulcer
Cryotherapy would destroy tissue without a diagnosis.
B. Incisional biopsy from the edge including adjacent normal mucosa (correct)
Correct. Tissue diagnosis from the edge is essential.
C. A trial of oral antibiotics only
Antibiotics may be added but will not exclude cancer.
D. Observation for 3 more months
Delaying for months risks progression of a probable carcinoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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