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Dermatology · Infections: bacterial, viral, fungal, parasitic: Vibrio vulnificus infection
Sample itemA 55-year-old man with alcoholic cirrhosis develops fever, hypotension and haemorrhagic bullae on the leg 24 hours after wading in seawater and eating raw oysters. Which organism is the likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Vibrio vulnificus
Vibrio vulnificus causes rapidly progressive haemorrhagic bullous cellulitis and septicaemia, especially in people with liver disease or iron overload. Doxycycline with a third-generation cephalosporin and early debridement are used.
Option by option
A. Erysipelothrix rhusiopathiae
Erysipelothrix causes an indolent violaceous cellulitis in fish handlers.
B. Vibrio vulnificus (correct)
Correct. Seawater or raw shellfish with cirrhosis and haemorrhagic bullae points to Vibrio vulnificus.
C. Mycobacterium marinum
Mycobacterium marinum causes indolent granulomas over weeks.
D. Streptococcus pyogenes
Group A streptococcus can cause necrotising infection but is not tied to seawater or oysters.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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