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Dermatology · Papulosquamous disorders: dimethylglyoxime test
Sample itemA woman has an itchy eczematous patch under the clasp of her wristwatch and around her navel under a jeans button. Which bedside test would confirm that the metal is the cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Dimethylglyoxime spot test turning pink
Nickel contact dermatitis causes eczema at sites of contact with metal objects. A dimethylglyoxime spot test turns pink in the presence of released nickel, and patch testing confirms sensitisation.
Option by option
A. Potassium hydroxide mount
A potassium hydroxide mount shows fungal elements and would not identify a metal allergen.
B. Dimethylglyoxime spot test turning pink (correct)
Correct. Dimethylglyoxime turns pink with released nickel.
C. Tzanck smear
A Tzanck smear looks for multinucleated giant cells in herpes or acantholytic cells in pemphigus.
D. Wood lamp examination of the patch
Wood lamp identifies fluorescent pigments or organisms and does not identify metal.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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