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Dermatology · Papulosquamous disorders: lichen planus malignant potential
Sample itemA 60-year-old with long-standing erosive oral lichen planus has a persistent firm, nonhealing ulcerated plaque on the lateral tongue. What is the most appropriate next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Biopsy of the lesion
Erosive oral lichen planus carries a small risk of squamous cell carcinoma. A persistent, indurated or ulcerated area needs biopsy, not escalation of local therapy.
Option by option
A. Oral antifungal therapy
An antifungal would not explain a firm nonhealing ulcer and does not address malignancy.
B. Increase topical steroid dose
More steroid risks delaying the diagnosis of a possible malignancy.
C. Biopsy of the lesion (correct)
Correct. A nonhealing indurated lesion in erosive lichen planus needs biopsy to exclude carcinoma.
D. Reassurance
Reassurance is unsafe for a lesion with suspicious features.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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