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Ophthalmology · Neuro-ophthalmology and pupils: traumatic optic neuropathy
Sample itemAn unconscious man after a road accident with a brow injury has a normal-looking fundus. Which sign most strongly suggests an indirect optic nerve injury?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Relative afferent pupillary defect
In traumatic optic neuropathy the disc appears normal at first, and pallor develops after weeks. An afferent pupillary defect is the key early sign, especially when the patient cannot be tested for vision. Proptosis and ptosis point to orbital or third nerve injury.
Option by option
A. Disc pallor on first examination
Disc pallor appears only weeks later.
B. Relative afferent pupillary defect (correct)
Correct. A relative afferent defect shows optic nerve dysfunction when the disc looks normal.
C. Ptosis
Ptosis suggests a third nerve or levator injury.
D. Proptosis
Proptosis suggests orbital haemorrhage or fracture, not the nerve injury itself.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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