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Dermatology · Infections: juvenile xanthogranuloma
Sample itemA 1-year-old has a solitary, firm, yellow-orange dome-shaped papule on the scalp. Biopsy shows Touton giant cells. Lipid profile is normal. What is the usual course?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Spontaneous regression over years
Juvenile xanthogranuloma is a benign non-Langerhans histiocytosis of infants and children with yellow-orange papules and Touton giant cells. Lipids are normal and lesions usually involute over 3 to 6 years. Ocular involvement in multiple lesions in infants warrants eye review.
Option by option
A. Indicates diabetes
It is not linked to diabetes.
B. Progression to lymphoma
It is benign and does not become lymphoma.
C. Spontaneous regression over years (correct)
Correct. Lesions usually regress spontaneously.
D. Needs lifelong statins
Lipid levels are normal, so statins are not needed.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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