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Dermatology · Papulosquamous disorders: prurigo nodularis
Sample itemA 55-year-old has intensely itchy, firm, hyperkeratotic nodules with excoriation on the extensor forearms and legs, sparing the mid upper back. Which diagnosis fits?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Prurigo nodularis
Prurigo nodularis forms firm excoriated nodules from chronic scratching, with sparing of unreachable skin (butterfly sign on the upper back). Treatment uses potent or intralesional steroids, with dupilumab as a newer systemic option. Underlying itch causes such as renal or liver disease should be sought.
Option by option
A. Nodular scabies only
Nodular scabies occurs on genitals and axillae with a scabies history.
B. Dermatofibroma
Dermatofibroma is a solitary asymptomatic firm nodule.
C. Prurigo nodularis (correct)
Correct. Excoriated nodules with butterfly-sign sparing indicate prurigo nodularis.
D. Hypertrophic lichen planus
Hypertrophic lichen planus has violaceous plaques on shins and shows Wickham striae.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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