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Pathology · Haemodynamics: Virchow triad
Sample itemA patient develops deep-vein thrombosis after prolonged immobilisation in hospital. Which component of Virchow triad is most directly responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Venous stasis
Immobility slows venous flow, allowing clotting factors to accumulate and reducing delivery of anticoagulant factors. Stasis is one of the three broad causes of thrombosis.
Option by option
A. Inherited thrombocytopenia
Thrombocytopenia causes bleeding rather than typical DVT.
B. Endothelial activation by turbulent flow
Turbulence is more important in arterial or cardiac thrombosis.
C. Systemic fibrinolysis
Fibrinolysis would oppose clot formation.
D. Venous stasis (correct)
Correct. Immobilisation is a classic cause of venous stasis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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