Acute inflammation: complement: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Acute inflammation: complement

Sample item

Which complement fragment is a powerful neutrophil chemotactic factor?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. C5a

C5a is a potent chemoattractant and activator of neutrophils. C3b is especially important for opsonization, while C5b-9 forms the membrane attack complex.

Option by option

  • A. C1q

    C1q initiates the classical complement pathway.

  • B. C5a (correct)

    Correct. C5a recruits and activates neutrophils.

  • C. C9 only

    C9 participates in the terminal membrane attack complex.

  • D. C3b

    C3b tags pathogens for phagocytosis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is B, C5a. C5a is a potent chemoattractant and activator of neutrophils.

Why is "C1q" not the answer?

C1q initiates the classical complement pathway.

Why is "C9 only" not the answer?

C9 participates in the terminal membrane attack complex.

Why is "C3b" not the answer?

C3b tags pathogens for phagocytosis.

What concept does this question test?

It tests Acute inflammation: complement in Pathology. C3b is especially important for opsonization, while C5b-9 forms the membrane attack complex.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Acute inflammation: complement?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.