Try it
Dermatology · STI: bowenoid papulosis
Sample itemA young sexually active man has multiple small, pigmented, flat-topped papules on the penile shaft. Biopsy shows full-thickness atypia resembling carcinoma in situ, but the lesions follow a benign course. Which virus is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. HPV 16
Bowenoid papulosis is associated with high-risk HPV 16 and histologically resembles Bowen disease, but behaves in a benign fashion and may regress. Long-term follow-up is required because of malignant potential, especially in partners.
Option by option
A. HPV 16 (correct)
Correct. HPV 16 is linked to bowenoid papulosis.
B. HHV-8
HHV-8 is associated with Kaposi sarcoma.
C. HSV-2
HSV-2 gives vesicles and ulcers.
D. HPV 6
HPV 6 gives ordinary genital warts.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Dermatology questions
- Blistering disordersA patient has flaccid blisters that rupture easily and a positive Nikolsky sign. Which c…
- LeprosyIn which type of leprosy is the lepromin test strongly positive?
- Pigmentary disordersA man has well-demarcated chalk-white macules on his hands and around his mouth. A skin…
- Drug reactionsWhich of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome an…