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Dermatology · STI: giant condyloma
Sample itemAn uncircumcised man has a large, locally destructive, cauliflower-like penile tumour caused by HPV 6 and 11, with deep invasion but no metastasis. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Buschke-Lowenstein tumour
Buschke-Lowenstein tumour, or giant condyloma, is a verrucous carcinoma of the anogenital region that invades locally and recurs, so wide surgical excision is the treatment. Podophyllin alone is not curative.
Option by option
A. Donovanosis
Donovanosis is an ulcerative granulomatous disease.
B. Bowenoid papulosis
Bowenoid papulosis consists of multiple small papules.
C. Buschke-Lowenstein tumour (correct)
Correct. A giant verrucous HPV 6/11 tumour is Buschke-Lowenstein tumour.
D. Erythroplasia of Queyrat
Erythroplasia of Queyrat is a velvety red plaque on the glans.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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