STI: treatment of gonorrhoea: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · STI: treatment of gonorrhoea

Sample item

Which regimen is the preferred treatment of uncomplicated gonococcal urethritis in most guidelines because of widespread quinolone resistance?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. A single intramuscular dose of ceftriaxone (a third-generation cephalosporin)

Resistance to penicillin, tetracyclines and fluoroquinolones is widespread, so third-generation cephalosporins are the mainstay, with azithromycin added where chlamydia is not excluded. In NACO syndromic care, cefixime 400 mg with azithromycin is used.

Option by option

  • A. Doxycycline alone for 7 days

    Doxycycline alone does not reliably cure gonorrhoea.

  • B. Penicillin G single dose

    Penicillin resistance is widespread.

  • C. Ciprofloxacin 500 mg single dose

    Quinolone resistance is widespread.

  • D. A single intramuscular dose of ceftriaxone (a third-generation cephalosporin) (correct)

    Correct. Ceftriaxone based therapy is preferred.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, A single intramuscular dose of ceftriaxone (a third-generation cephalosporin). Resistance to penicillin, tetracyclines and fluoroquinolones is widespread, so third-generation cephalosporins are the mainstay, with azithromycin added where chlamydia is not excluded.

Why is "Doxycycline alone for 7 days" not the answer?

Doxycycline alone does not reliably cure gonorrhoea.

Why is "Penicillin G single dose" not the answer?

Penicillin resistance is widespread.

Why is "Ciprofloxacin 500 mg single dose" not the answer?

Quinolone resistance is widespread.

What concept does this question test?

It tests STI: treatment of gonorrhoea in Dermatology. In NACO syndromic care, cefixime 400 mg with azithromycin is used.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study STI: treatment of gonorrhoea?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.