Inflammation: chemotaxis: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Inflammation: chemotaxis

Sample item

Which mediator is a major chemoattractant for neutrophils in acute inflammation?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Interleukin-8

IL-8 is a chemokine that attracts and activates neutrophils. Other chemotactic factors include C5a, leukotriene B4, and bacterial products.

Option by option

  • A. Interleukin-4

    IL-4 promotes Th2 responses and alternative macrophage activation.

  • B. Transforming growth factor-beta only

    TGF-beta has diverse regulatory and fibrotic effects.

  • C. Interleukin-8 (correct)

    Correct. IL-8 is a key neutrophil chemokine.

  • D. Erythropoietin

    Erythropoietin stimulates erythroid progenitors.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Interleukin-8. IL-8 is a chemokine that attracts and activates neutrophils.

Why is "Interleukin-4" not the answer?

IL-4 promotes Th2 responses and alternative macrophage activation.

Why is "Transforming growth factor-beta only" not the answer?

TGF-beta has diverse regulatory and fibrotic effects.

Why is "Erythropoietin" not the answer?

Erythropoietin stimulates erythroid progenitors.

What concept does this question test?

It tests Inflammation: chemotaxis in Pathology. Other chemotactic factors include C5a, leukotriene B4, and bacterial products.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Inflammation: chemotaxis?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.